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Horses
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5 ml per 100 kg bodyweight by intravenous injection only
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Adult Cattle
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5 ml per 100 kg bodyweight by intravenous or intramuscular injection
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Dogs
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0.1 ml per kg bodyweight by intravenous or intramuscular injection
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CONTRAINDICATIONS:
Due to a risk of local reactions, do not use the intramuscular route in horses.
Do not use in pregnant animals as safety during pregnancy in the target species has not been established.
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Do not use in horses suffering from paralytic ileus.
Special precautions for use in animals:
In horses, a slight transient increase in heart rate may be observed due to the parasympatholytic activity of butylscopolamine bromide.
Special Precautions to be taken by the person administering the product to animals:
Take care to avoid self-injection. In a very small number of people, metamizole can cause reversible, but potentially serious agranulocytosis and other reactions such as skin allergy. Avoid use of the product if you are known to be sensitive to pyrazolones, or are sensitive to aspirin. Wash any splashes from the skin. If accidental self-injection occurs, seek medical advice and show the Doctor the product packaging.
Studies in laboratory animals (rabbit, rat) have not produced any evidence of a teratogenic effect. No information on use during pregnancy in the target species is available and therefore this product should not be used.
The effects of metamizole and/or butylscopolamine bromide may be potentiated by concurrent use of other anticholinergic or analgesic drugs.
The acute toxicity of both compounds is very low. In studies with rats, the symptoms were non-specific and included ataxia, mydriasis, tachycardia, prostration, convulsions, coma and respiratory signs.
Symptomatic treatment should be initiated in case of overdosage.
WITHDRAWAL PERIOD:
Animals should not be slaughtered for human consumption during treatment.
Meat and offal:
Horses - 12 days
Cattle - 9 days after intravenous injection, 28 days after intramuscular injection.
Do not use in cows producing milk for human consumption.
