Enzaprost 5 mg/ml solution for injection for cattle and pigs 30ml.
Enzaprost® is indicated for its luteolytic effects in cattle and pigs.
The indications for use are:
Cattle:
1. Oestrus synchronisation.
2. Treatment of sub-oestrus or silent heat in cows which have a functional corpus luteum, but do not express behavioural oestrus.
3. Induction of abortion until day 120 of pregnancy.
4. Induction of parturition.
5. As an aid in the treatment of chronic metritis or pyometra where there is a functional or persistant corpus luteum.
Pigs:
1. Induction of parturition from day 111 of pregnancy.
2. Post partum use: reduction of the weaning to oestrus interval (WOI) and the weaning to fertile service interval (WFSI) in sows with puerperal problems such as metritis in herds with reproductive problems.
Dosage and administration
A single injection of the recommended dose of dinoprost activity is luteolytic provided a functional corpus luteum is present. Administer by intramuscular injection.
Full aseptic precautions should be taken. Use a sterile syringe and needle and make the injection through an area of clean skin. Care should be taken to avoid injection through wet or dirty areas of skin.
Cattle
The dose rate for all indicated uses in cattle is 5 ml Enzaprost® (25 mg dinoprost).
1. Oestrus synchronisation One administration of 25 mg of dinoprost (as trometamol), ie 5 ml of the product per animal, to be repeated, if necessary after 11 (10 to 12) days. Animals treated during dioestrus will normally return to oestrus and ovulate within two to four days after treatment. Animals treated with the product may be bred by natural service, artificial insemination on detected oestrus or at fixed time insemination (72 and 96 hours after the second injection is usually recommended).
2. Treatment of sub-oestrus or silent heat in cows which have a functional corpus luteum, but do not express behavioural oestrus.
One administration of 25 mg of dinoprost (as trometamol), ie 5 ml of the product per animal, to be repeated, if necessary after 11 (10 to 12) days.
3. Induction of abortion until day 120 of pregnancy
One administration of 25 mg of dinoprost (as trometamol), ie 5 ml of the product per animal. The product may be used to terminate pregnancy in cattle until day 120 of pregnancy through its luteolytic effect.
4. Induction of parturition
One administration of 25 mg of dinoprost (as trometamol), ie 5 ml of the product per animal on or after day 270 of gestation. The interval from administration to parturition is one to eight days (average three days).
5. For the aid in the treatment of chronic metritis or pyometra where there is a functional or persistent corpus luteum.
One administration of 25 mg of dinoprost (as trometamol), ie 5 ml of the product per animal, to be repeated, if necessary after 11 (10 to 12) days.
Pigs
1. Induction of parturition: One administration of 10 mg of dinoprost (as trometamol), ie 2 ml of the product per animal within 3 days of expected parturition. Response to treatment by individual animals varies within a range of 24-36 hours from administration to parturition. This can be used to control the time of farrowing in sows and gilts in late gestation. Treatment earlier than 3 days prior to predicted farrowing date may induce weak piglets.
2. Post-partum use: One administration of 10 mg of dinoprost (as trometamol), ie 2 ml of the product per animal 24 to 36 hours after parturition.
