Vanguard Plus CPV

VANGUARD Plus CPV is a high-titer, modified-live canine parvovirus (CPV) strain attenuated by low passage on an established canine cell line. The combination of high titer and low passage gives VANGUARD Plus CPV the immunogenic properties capable of stimulating active immunity in the presence of maternal antibodies. Some puppies in the field may have higher levels of maternal antibodies than those evaluated in our pivotal efficacy study.

• Inherently greater immunogenicity of a low-passage CPV produced at high titer can help stimulate active immunity in the presence of maternal antibodies. Serum neutralization titers as low as 1:4 have been shown to prevent active immunization by conventional vaccines. VANGUARD Plus CPV has been shown to successfully immunize dogs with pre-vaccination serum neutralization (SN) titers, some as high as 1:64.
• Customer-friendly packaging includes peel-off labels to make record-keeping faster and more accurate, a color-coded organizing system, and an easy-open safety band.
• VANGUARD Plus CPV is supported by our Companion Animal Immunization Support Guarantee (ISG).
• DIRECTIONS:
  
  1. General Directions: Vaccination of healthy dogs is recommended. Shake well. Aseptically administer 1 mL subcutaneously or intramuscularly.
  
  2. Primary Vaccination: Healthy dogs 6 weeks of age or older should receive 3 doses, each administered 3 weeks apart.
  
  3. Revaccination: Annual revaccination with a single dose is recommended, although, as recommended by the American Veterinary Medical Association and its Council on Biologic and Therapeutic Agents, the attending veterinarian should determine the frequency of revaccination based on the animal's lifestyle and risk of exposure.