Description
1 ml solution containing 0.25 mg of cloprostenol (sodium salt). Cloprostenol – synthetic analogue of prostaglandin F2a function has a specific lyuteoliticheskim action. Its application in the phase of the estrous cycle lyuteralnoy causes the disappearance of the corpus luteum and thus creates the preconditions for the onset of estrus and ovulation. Period of drug administration until the first signs of advancing oestrus lasts 48-60 hours. The most suitable time for Artificial insemination is about 76 hours after administration (in mares whichever occurs 24 hours later). Acts specifically lyuteoliticheski, causing the death of the corpus luteum and thus creating the preconditions for oestrus and ovulation in 48 – 60 hours after drug administration.
Indications
synchronization call and estrus in heifers and cows and mares. Induktirovanie farrowing sows. At large and small ruminants: functional disorders of the ovaries, and postpartalny postservisny anestrus (Silent estrus, impaired frequency cycle; anovulyatsionny cycle; persistuyuschee corpus luteum cyst lyuteralnaya) postpuerperalnye diseases of the uterus, endometritis, uterine suppuration; interruption of normal and abnormal pregnancy (in first half of pregnancy), combination therapy folekulyarnyh cysts (10 days after HCG or LHRH, after the establishment of a positive ovarian response). In mares: anestrus (silent estrus, diestrus persistuyuschy, fetal abortions, lactational anestrus, interruption of pseudopregnant); cessation of normal and pathological pregnancy (in the first half pregnancy).
CONTRAINDICATIONS AND WARNINGS
have been a little mares sweating, which disappears within one hour after administration. Within 24 hours after drug administration animals can not be supplied to the slaughterhouse. Milk cows with the administration of drugs can be used for food purposes without limitations.
DOSAGE
0,7-2 ml of the drug in a one-time depending on the evidence and species. The drug is administered intramuscularly and 2 ml 2 times with an interval of 10 days. The first introduction – in any phase of the sexual cycle (in cows from 40 th to 60 th day after birth). The drug is administered intramuscularly. Artificial Insemination advisable to carry out the cows in 76 hours after drug administration, the mares at 24 h later.
large and small ruminants:
Synchronizing estrus :
2 ml of the drug administered (0.50 mg of active substance), 2 times in the range of 10 days. The first dose is administered in any phase of the sexual cycle (in cows in period of 40-60 days after calving). On the 11th day after the first applications are introduced second dose, the 14th day (72-76 hours after the second dose) performed artificial insemination (despite no external signs of estrus), followed by re- artificial insemination (15th day). Before each use of the drug for synchronization in cattle should be preceded by examination of sexual organs. A prerequisite for inclusion in the group of animals is a physiological condition their genital organs, the heifers their bodily and sexual maturity.
Functional disorders of the ovaries :
Injected 2 ml of the drug, artificial insemination is performed at first estrus. If the chute does not occur, the drug is administered repeatedly at a dose of 2 ml at day 11 after the first application, followed by artificial insemination at 72 – 76 need to spend hours on re-insemination. For the treatment of folekulyarnyh cysts injected 2ml single dose of the drug, not earlier than the 10th day after HCG or LHRH after the establishment of a positive ovarian response. Estrus also occurs in the third day after the injection of a solution for Estrofana injection.
Postpuerperalnye diseases of the uterus:
Injected 2 ml of the drug treatment needs to be supplemented intrauterinnoy applique products in the form of foam or washing (preferably at the same time applique), the 11th day – re-application, 14th day – artificial insemination, 15th day – re-insemination.
Abortion:
Injected 2 ml of the drug (further care depending on the clinical state).
Sows:
A single dose of 0.7 ml composes drug (0.175 mg of active substance) introduced by 111 days of gestation. Most of the induced farrowing occurs before 40 hours of injection with the culmination of between 24 -35 hours.
Mares:
A single dose of 1 ml of the drug (0.25 mg of active ingredient). Y mares with the cycle of drug administered during the period from 5 to 13 days after estrus. The most suitable for mating period is 4.6 days after application.
